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14 Factors Contributing to Serotonin Syndrome

5. Inhibitors of monoamine oxidase

Evidently, there are a variety of medications that can induce serotonin syndrome. On the list of potential causes of serotonin syndrome, MAOIs (monoamine oxidase inhibitors) are also included. These medications are utilized to treat a variety of psychological disorders. Additionally, they are used to treat Parkinson’s disease. MAOIs operate by inhibiting monoamine oxidase production. Monoamine oxidase is responsible for the breakdown of numerous substances and neurotransmitters in the body and brain.

Included in this is serotonin. The use of an MAOI increases the availability of serotonin in the brain. If this continues for too long, you may develop the undesirable and potentially hazardous symptoms of serotonin syndrome. If you are prescribed an MAOI for a mood disorder and begin experiencing symptoms of serotonin syndrome, it is imperative that you discuss these concerns with your doctor.

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